pork chops cook relatively quickly in the crock pot. cook thick cut boneless pork chops for 1 1/2 to 3 hours on the slow cooker's low setting. when i tested this recipe with 1-inch thick boneless pork chops, they took 1 1/2 to 2 hours to cook through. if using bone-in pork chops, they will take 2 1/2 to 3 hours on low.